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Objective:To explore the clinical efficacy of computer-assisted cognitive training in the treatment of cognitive impairment after stroke.Methods:A total of 155 stroke survivors with vascular cognitive impairment were identified at 31 hospitals. They were randomly divided into a control group of 72 and an experimental group of 77 (6 failed to follow up). The control group received 30 minutes of conventional cognition training 5 times a week for 2 weeks, while the experimental group was given computer-assisted cognition training. Before and after the treatment, both groups′ cognition was evaluated using Chinese versions of the Mini Mental State Assessment Scale (MMSE) and the Montreal Cognitive Test (MoCA).Results:After the treatment, the average MMSE and MoCA scores of the observation group [(22.5±3.62) and (19.69±4.43)] and the control group [(21.7±4.30) and (19.10±5.58)] were significantly better than those before the treatment [(19.3±3.08) and (16.79±4.58); (19.7±3.11) and (17.74±5.25)]. The post-treatment difference between the groups′ averages was not significant, but the observation group′s improvements on the immediate memory, delayed memory and calculation portions of the MMSE were significantly greater than those of the control group.Conclusions:Computer-assisted cognition training can improve the overall cognitive functioning of stroke survivors, achieving the same therapeutic effect as conventional cognitive therapy. It is more effective than conventional cognitive therapy in promoting immediate memory, delayed memory and calculation ability.
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Objective:To explore the effect of combining hyperbaric oxygen (HBO) therapy with cognition training for persons with vascular cognitive impairment (VCI).Methods:Forty-two persons with VCI were randomly divided into a control group of 19 and a research group of 23. In addition to basic treatment, the control group was given hyperbaric oxygen therapy once a day, 5 days per week for 4 weeks, while the research group received cognition training along with the hyperbaric oxygen therapy. Each person′s cognition was assessed using the Simple Mental Status Scale (MMSE) before and after the four-week treatment. Meanwhile, 3ml of venous blood was collected before eating in the morning to test the plasma levels of Klotho protein and homocysteine using enzyme-linked immunosorbent assays.Results:After the treatment the average MMSE score had improved significantly in both group, with the improvement in the research group′s average significantly greater than that in the control group. The average plasma levels of Klotho protein and homocysteine had also improved significantly more in the research group. In the control group, the only significant improvement was in the average homocysteine level.Conclusions:Hyperbaric oxygen therapy can be an effective supplement to cognition training for persons with vascular cognitive impairment.
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To prove the hypothesis of facial feedback (FF) for opposite emotional stimuli, 30 participants viewed a happy video, with 15 of the participants posing a sad expression; another 30 participants viewed a sad video, with 15 posing a joyful expression. Levels of joy, sadness, anger and anxiety were recorded before and after the videos. All observers of the happy video showed a decrease in sadness, but those who posed for sadness expressed lesser decrease. For their part, participants who posed joy during the sad video recorded an increase in anger and anxiety, attributed to having to pose for joy. No evidence was found that FF can counteract the effects of an intense emotional stimulus. The evidence related to the controlling of the intensity of an opposite emotion was also limited. The study found that posing for joy while undergoing sadness could provoke other negative emotions. The study questions the practical usefulness of FF.
Con el objetivo de probar la hipótesis del feedback facial (FF) para estímulos emocionales opuestos, 30 participantes vieron un video feliz, 15 posando una expresión triste; y otros 30 participantes vieron un video triste, 15 posando una expresión de alegría. Se registraron los niveles de alegría, tristeza, ira y ansiedad antes y después de ver los videos. Todos los participantes que vieron el video feliz mostraron una disminución en la tristeza, pero aquellos que posaron tristeza durante el mismo, mostraron una disminución menor. Por su parte, los participantes que posaron alegría durante el video triste indicaron un aumento de la ira y la ansiedad, atribuido a tener que posar alegría. No se encontró evidencia de que el FF pueda contrarrestar los efectos de un estímulo emocional intenso. La evidencia relacionada con la regulación de la intensidad de una emoción opuesta, también fue limitada. Se encontró que posar alegría durante la experimentación de tristeza, podría provocar otras emociones negativas. Se cuestiona la utilidad práctica del FF.
Com o objetivo de provar a hipótese do feedback facial (FF) para estímulos emocionais opostos, 30 participantes assistiram a um vídeo feliz, dos quais 15 posaram com uma expressão triste, e outros 30 participantes viram um vídeo triste, dos quais 15 posaram com uma expressão de alegria. Registraram-se os níveis de alegria, tristeza, ira e ansiedade antes e depois de assistir aos vídeos. Todos os observadores do vídeo feliz mostraram uma diminuição na tristeza, mas os que posaram tristeza durante esse vídeo expressaram uma diminuição menor. Por sua vez, os participantes que posaram alegria durante o vídeo triste registraram um aumento de ira e ansiedade, atribuído a ter que demonstrar alegria. Não se constatou evidência de que o FF possa neutralizar os efeitos de um estímulo emocional intenso. A evidência relacionada com a regulação da intensidade de uma emoção oposta também foi limitada. Constatou-se que posar alegria durante uma experiência de tristeza poderia provocar outras emoções negativas. Questiona-se a utilidade da prática do FF.
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Objective To observe the effect of cognition training on the motor and executive functioning of patients after a basal ganglia stroke.Methods Thirty patients with basal ganglia stroke were randomly divided into a treatment group and a control group.The control group received standard stroke rehabilitation training,while the treatment group received in addition 2 months of cognitive function training.The executive and motor functions of all of the subjects and their facility in the activities of daily living (ADL) were tested using the Tower of Hanoi,the Wisconsin card sorting test,a Stroop-3 test and the Fugl-Meyer assessment,the Berg balance scale and the modified Barthel index before and at the end of treatment.Results After two months of training,both within-group and between group comparisons showed that the treatment group had improved significantly more in executive function,cognition and motor function.Conclusion Cognition training can improve executive function,motor function and ADL performance after a basal ganglia stroke.
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@#ObjectiveTo explore the influence of cluster needling of scalp acupuncture combined with rehabilitation techniques on cognition dysfunction in patients with cerebral infarction.Methods60 patients with cerebral infarction following cognitive impairment were randomly divided into 3 groups: Group A (the cluster needling of scalp acupuncture), group B (cognition training) and group C (cluster needling of scalp acupuncture combined with cognition training). All groups received routine neuropathic treatment. All patients were assessed by the Mini-Mental State Examination (MMSE) before and a month after treatment. The therapeutic effect was observed by change of P300 latency and solid contents of blood plasma cortisol a month after the treatment.ResultsThere was significant difference in the score of MMSE, P300 latency, and solid contents of blood plasma cortisol in 3 groups before and after the treatment(P<0.05). Compared to groups A and B, group C got a higher score of MMSE, shorter latency of P300 and lower solid contents of blood plasma cortisol (P＜0.01). ConclusionCluster needling of scalp acupuncture combined with cognition training may reduce solid contents of blood plasma cortisol and improve cognition function in patients with cerebral infarction.